INDICATIONS AND Use OXYCONTIN is definitely an opioid agonist indicated for your administration of severe and persistent suffering that requires an extended treatment method time period using a every day opioid analgesic and for which choice procedure selections are insufficient in:(1) Grownups; and
Use the bottom helpful dosage to the shortest period of time consistent with unique individual treatment objectives [see Warnings and Safety measures (5)]. Because the danger of overdose boosts as opioid doses enhance, reserve titration to higher doses of OXYCONTIN for patients in whom decrease doses are insufficiently helpful As well as in whom the predicted advantages of working with an increased dose opioid clearly outweigh the sizeable challenges.
Oxycodone needs to be applied with caution plus the dosage might should be lessened in clients applying these drugs.
The suggested Grownup commencing dose ought to be lowered by fifty% (for example a total day by day dose of ten mg orally in opioid naï ve patients), and every affected person really should be titrated to adequate agony Handle In keeping with their scientific scenario.
Makers of the brand-name drug can provide their drug for approximately twenty years. If the patent for any brand-title drug expires, other drug producers will make and sell generic variations.
• OxyContin is usually a federally controlled material (CII) mainly because it is a strong opioid ache medicine that can be abused by those who abuse prescription medicines or street medicine.
Ask your medical professional or pharmacist if you need to have naloxone available to deal with opioid overdose. Instruct All your read more family members or residence customers regarding the signs of an opioid overdose and the way to treat it.
Serotonin syndrome: Instances of serotonin syndrome, a probably existence-threatening ailment, are actually claimed during concomitant usage of opioids with serotonergic medications.
This solution may possibly have inactive elements, that may lead to allergic reactions or other troubles. Talk with your pharmacist for more information.
To study the offered strengths of the generic and model-identify versions of oxycodone, see the chart during the “FAQs about Value and oxycodone” segment higher than.
This Level of competition might aid hold expenditures of generic prescription drugs decreased. Also, generic medications include the exact same active drugs as manufacturer-name medications. So that they don’t require the exact same testing, which can be costly.
Lessened physique excess weight was uncovered for the duration of lactation as well as early post-weaning phase in pups nursed by mothers presented the highest dose utilised (six mg/kg/working day, reminiscent of an Grownup human dose of 60 mg/day, on a mg/m2 foundation). On the other hand, human body weight of those pups recovered.
If the doctor has prescribed oxycodone therefore you’re enthusiastic about using a brand name-identify drug alternatively, talk with your doctor.
When working with OXYCONTIN with CYP3A4 inducers or discontinuing CYP3A4 inhibitors, Consider patients at Recurrent intervals and think about rising the opioid dosage if wanted to maintain satisfactory analgesia or if indicators of opioid withdrawal take place [see Drug Interactions (seven)].